mouse IER3 shRNA silencing Adenovirus

Name 
Ad-m-IER3-shRNA
Cat No 
shADV-261862
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Ier3.

shADV-261862
Ad-m-IER3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ier3 (immediate early response 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI663993; cI-3; gly96; IEX-1
Description (Vector)
IER3 may play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival.
Gene ID
15937
Gene Name (Vector)
immediate early response 3
Gene Symbol
Ier3
ORF Size (aa)
483
RefSeq ID
NM_133662
RefSeq Synonyms
NM_133662, BC006950,
Species
mouse
UniGene ID
Mm.25613

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.