mouse HS3ST5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Hs3st5.
shADV-261675
Ad-m-HS3ST5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hs3st5 (heparan sulfate (glucosamine) 3-O-sulfotransferase 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D930005L05Rik; Gm1151; Hs3ost5
Description (Vector)
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site. Also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry.
Gene ID
319415
Gene Name (Vector)
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
Gene Symbol
Hs3st5
ORF Size (aa)
1041
RefSeq ID
NM_001081208
RefSeq Synonyms
NM_001253356, NM_001253355, NM_001081208, BC158004, BC150973, BC147493, BC147490,
Species
mouse
UniGene ID
Mm.332442
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.