mouse HLTF shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse HLTF.
shADV-261433
Ad-m-HLTF-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse HLTF (helicase-like transcription factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AF010600; BC057116; P113; Smarca3; Snf2l3;
Description (Vector)
Has both helicasee and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
Gene ID
20585
Gene Name (Vector)
helicase-like transcription factor
Gene Symbol
HLTF
ORF Size (aa)
3012
ORF Size (bp)
3012 bp
RefSeq ID
NM_009210
RefSeq Synonyms
NM_144959, NM_009210, BC059240, BC057116,
Species
mouse
UniGene ID
Mm.209650
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.