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mouse GRPEL2 shRNA silencing Adenovirus

Name 
Ad-m-GRPEL2-shRNA
Cat No 
shADV-260803
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Grpel2.

shADV-260803
Ad-m-GRPEL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Grpel2 (GrpE-like 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
mt-GrpE#2; mt-Grpel2
Description (Vector)
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity).
Gene ID
17714
Gene Name (Vector)
GrpE-like 2, mitochondrial
Gene Symbol
Grpel2
ORF Size (aa)
675
ORF Size (bp)
675 bp
RefSeq ID
NM_021296
RefSeq Synonyms
NM_021296, BC120747, BC068232,
Species
mouse
UniGene ID
Mm.269657

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.