mouse GRIA1 shRNA silencing Adenovirus

Name 
Ad-m-GRIA1-shRNA
Cat No 
shADV-260749
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Gria1.

shADV-260749
Ad-m-GRIA1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Gria1 (glutamate receptor, ionotropic, AMPA1 (alpha 1)). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2900051M01Rik; Glr-1; Glr1; GluA1; Glur-1; GluR-A; gluR-K1; Glur1; GluRA; HIPA1
Description (Vector)
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Gene ID
14799
Gene Name (Vector)
glutamate receptor, ionotropic, AMPA1 (alpha 1)
Gene Symbol
Gria1
ORF Size (aa)
2724
ORF Size (bp)
2724 bp
RefSeq ID
NM_008165
RefSeq Synonyms
NM_008165, NM_001252403, NM_001113325, BC056397,
Species
mouse
UniGene ID
Mm.4920

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.