mouse GRB7 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Grb7.
shADV-260739
Ad-m-GRB7-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Grb7 (growth factor receptor bound protein 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
mKIAA4028
Description (Vector)
Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity).
Gene ID
14786
Gene Name (Vector)
growth factor receptor bound protein 7
Gene Symbol
Grb7
ORF Size (aa)
1608
ORF Size (bp)
1608 bp
RefSeq ID
NM_010346
RefSeq Synonyms
NM_010346, BC003295,
Species
mouse
UniGene ID
Mm.276702
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.