human MIP Over-expression AAV

Name 
AAV-h-MIP
Cat No 
AAV-215480
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MIP.

AAV-215480
AAV-h-MIP

Ready-to-use AAV expressing Human MIP (major intrinsic protein of lens fiber). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AQP0; CTRCT15; LIM1; MIP26; MP26
Description (Vector)
Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13.
Gene ID
4284
Gene Name (Vector)
major intrinsic protein of lens fiber
Gene Symbol
MIP
HGNC ID
HGNC:7103
ORF Size (aa)
792
ORF Size (bp)
792 bp
RefSeq ID
NM_012064
RefSeq Synonyms
NM_012064, BC117474, BC074913,
Species
human
UniGene ID
Hs.574026

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.