human MGP Over-expression AAV

Name 
AAV-h-MGP
Cat No 
AAV-215427
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MGP.

AAV-215427
AAV-h-MGP

Ready-to-use AAV expressing Human MGP (matrix Gla protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GIG36; MGLAP; NTI
Description (Vector)
MGP is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS). Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
4256
Gene Name (Vector)
matrix Gla protein
Gene Symbol
MGP
HGNC ID
HGNC:7060
ORF Size (aa)
312
RefSeq ID
NM_000900
RefSeq Synonyms
NM_001190839, NM_000900, BC093078, BC070314, BC005272,
Species
human
UniGene ID
Hs.365706

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.