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human TNFRSF10C Over-expression AAV

Name 
AAV-h-TNFRSF10C
Cat No 
AAV-215412
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TNFRSF10C.

AAV-215412
AAV-h-TNFRSF10C

Ready-to-use AAV expressing Human TNFRSF10C (TNF receptor superfamily member 10c). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD263; DCR1; DCR1-TNFR; LIT; TRAIL-R3; TRAILR3; TRID
Description (Vector)
TNFRSF10C is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
Gene ID
8794
Gene Name (Vector)
TNF receptor superfamily member 10c
Gene Symbol
TNFRSF10C
HGNC ID
HGNC:11906
ORF Size (aa)
780
RefSeq ID
NM_003841
RefSeq Synonyms
NM_003841, BC125042, BC125041,
Species
human
UniGene ID
Hs.655801

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.