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mouse FANCL shRNA silencing Adenovirus

Name 
Ad-m-FANCL-shRNA
Cat No 
shADV-259150
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Fancl.

shADV-259150
Ad-m-FANCL-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Fancl (Fanconi anemia, complementation group L). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2010322C19Rik; AW554273; B230118H11Rik; gcd; Phf9; Pog
Description (Vector)
Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth.
Gene ID
67030
Gene Name (Vector)
Fanconi anemia, complementation group L
Gene Symbol
Fancl
ORF Size (aa)
1128
RefSeq ID
NM_025923
RefSeq Synonyms
NM_025923, NM_001277273, BC066181, BC032876,
Species
mouse
UniGene ID
Mm.18875

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.