mouse FAM123A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Amer2.
shADV-258946
Ad-m-FAM123A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Amer2 (APC membrane recruitment 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2600011E07Rik; Fam123a
Description (Vector)
Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.
Gene ID
72125
Gene Name (Vector)
APC membrane recruitment 2
Gene Symbol
Amer2
ORF Size (aa)
1419
ORF Size (bp)
1419 bp
RefSeq ID
NM_028113
RefSeq Synonyms
NM_028113, NM_001164705, BC056350,
Species
mouse
UniGene ID
Mm.275499
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.