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mouse EYA4 shRNA silencing Adenovirus

Name 
Ad-m-EYA4-shRNA
Cat No 
shADV-258819
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Eya4.

shADV-258819
Ad-m-EYA4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Eya4 (EYA transcriptional coactivator and phosphatase 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
B130023L16Rik
Description (Vector)
Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity).
Gene ID
14051
Gene Name (Vector)
EYA transcriptional coactivator and phosphatase 4
Gene Symbol
Eya4
ORF Size (aa)
1851
ORF Size (bp)
1851 bp
RefSeq ID
NM_010167
RefSeq Synonyms
NM_010167, NM_001347372, BC120899, BC120898,
Species
mouse
UniGene ID
Mm.446298

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.