mouse EPC1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Epc1.
shADV-258555
Ad-m-EPC1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Epc1 (enhancer of polycomb homolog 1 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2400007E14Rik; 5730566F07Rik; A930032N02Rik; mir-1893
Description (Vector)
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
Gene ID
13831
Gene Name (Vector)
enhancer of polycomb homolog 1 (Drosophila)
Gene Symbol
Epc1
ORF Size (aa)
2442
ORF Size (bp)
2442 bp
RefSeq ID
NM_027497
RefSeq Synonyms
NM_027497, NM_007935, NM_001276350, BC138623, BC138622,
Species
mouse
UniGene ID
Mm.312133
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.