human METAP1 Over-expression AAV

Name 
AAV-h-METAP1
Cat No 
AAV-215320
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human METAP1.

AAV-215320
AAV-h-METAP1

Ready-to-use AAV expressing Human METAP1 (methionyl aminopeptidase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MAP 1; MAP1A; metAP 1; MetAP1A; methionine aminopeptidase 1; peptidase M 1
Description (eCommerce)
Methionine aminopeptidase 1 (METAP1) cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). It is required for normal progression through the cell cycle [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P53582].
Gene ID
23173
Gene Name (eCommerce)
methionyl aminopeptidase 1
Gene Name (Vector)
methionyl aminopeptidase 1
Gene Symbol
METAP1
HGNC ID
HGNC:15789
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
819
ORF Size (bp)
819 bp
Protein Name (eCommerce)
Methionine aminopeptidase 1
RefSeq ID
NM_015143
RefSeq Synonyms
NM_015143, BC030054,
Research Areas
Neurobiology,Signal Transduction,Translational Control
Research Areas (Faceted)
cell_biology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Methionine aminopeptidase 1 (METAP1) cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). It is required for normal progression through the cell cycle [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P53582].
UniGene ID
Hs.480364
UniProt ID (eCommerce)
P53582

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.