mouse EIF2A shRNA silencing Adenovirus

Name 
Ad-m-EIF2A-shRNA
Cat No 
shADV-258179
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Eif2a.

shADV-258179
Ad-m-EIF2A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Eif2a (eukaryotic translation initiation factor 2A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
D030048D22; D3Ertd194e
Description (Vector)
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.
Gene ID
229317
Gene Name (Vector)
eukaryotic translation initiation factor 2A
Gene Symbol
Eif2a
ORF Size (aa)
1464
ORF Size (bp)
1464 bp
RefSeq ID
NM_001005509
RefSeq Synonyms
NM_001005509, BC082557, BC030447,
Species
mouse
UniGene ID
Mm.21617

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.