mouse PTBP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ptbp1.
shADV-257642
Ad-m-PTBP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ptbp1 (polypyrimidine tract binding protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA407203; AL033359; HNRPI; pPTB; Ptb; PTB-1; PTB2; PTB3; PTB4
Description (Vector)
Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10.
Gene ID
19205
Gene Name (Vector)
polypyrimidine tract binding protein 1
Gene Symbol
Ptbp1
ORF Size (aa)
1668
ORF Size (bp)
1668 bp
RefSeq ID
NM_008956
RefSeq Synonyms
NM_008956, NM_001283013, NM_001077363, BC086489, BC066210, BC028848, BC007472,
Species
mouse
UniGene ID
Mm.265610
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.