mouse DYNC1I2 shRNA silencing Adenovirus

Name 
Ad-m-DYNC1I2-shRNA
Cat No 
shADV-257568
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Dync1i2.

shADV-257568
Ad-m-DYNC1I2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dync1i2 (dynein cytoplasmic 1 intermediate chain 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
3110079H08Rik; AW554389; Dncic2
Description (Vector)
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.
Gene ID
13427
Gene Name (Vector)
dynein cytoplasmic 1 intermediate chain 2
Gene Symbol
Dync1i2
ORF Size (aa)
1839
ORF Size (bp)
1839 bp
RefSeq ID
NM_010064
RefSeq Synonyms
NM_010064, NM_001347173, NM_001198878, NM_001198877, NM_001198876, NM_001198875, NM_001198874, NM_001198873, NM_001198872, BC139375, BC139374,
Species
mouse
UniGene ID
Mm.249479

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.