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mouse DTX2 shRNA silencing Adenovirus

Name 
Ad-m-DTX2-shRNA
Cat No 
shADV-257499
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Dtx2.

shADV-257499
Ad-m-DTX2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dtx2 (deltex 2, E3 ubiquitin ligase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2610524D08Rik; AA408415; AU022494; Deltex2
Description (Vector)
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Gene ID
74198
Gene Name (Vector)
deltex 2, E3 ubiquitin ligase
Gene Symbol
Dtx2
ORF Size (aa)
1074
ORF Size (bp)
1074 bp
RefSeq ID
NM_023742
RefSeq Synonyms
NM_023742, NM_001256098, NM_001256097, NM_001256096, BC024925,
Species
mouse
UniGene ID
Mm.275574

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.