mouse DNAJC2 shRNA silencing Adenovirus

Name 
Ad-m-DNAJC2-shRNA
Cat No 
shADV-257306
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Dnajc2.

shADV-257306
Ad-m-DNAJC2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dnajc2 (DnaJ heat shock protein family (Hsp40) member C2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AU020218; MIDA1; Zrf1; Zrf2
Description (Vector)
Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation. Specifically binds DNA sequence 5'-GTCAAGC-3'.
Gene ID
22791
Gene Name (Vector)
DnaJ heat shock protein family (Hsp40) member C2
Gene Symbol
Dnajc2
ORF Size (aa)
1866
ORF Size (bp)
1866 bp
RefSeq ID
NM_009584
RefSeq Synonyms
NM_009584, BC052027,
Species
mouse
UniGene ID
Mm.266312

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.