mouse DCUN1D1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Dcun1d1.
shADV-256876
Ad-m-DCUN1D1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dcun1d1 (DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
pTes3; Rp42; SCCRO; Tes3
Description (Vector)
Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression (By similarity).
Gene ID
114893
Gene Name (Vector)
DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
Gene Symbol
Dcun1d1
ORF Size (aa)
780
RefSeq ID
NM_033623
RefSeq Synonyms
NM_033623, NM_001205362, NM_001205361, BC037431, BC031666, BC020161,
Species
mouse
UniGene ID
Mm.474495
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.