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human MCC Over-expression AAV

Name 
AAV-h-MCC
Cat No 
AAV-215155
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MCC.

AAV-215155
AAV-h-MCC

Ready-to-use AAV expressing Human MCC (mutated in colorectal cancers). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MCC1
Description (Vector)
MCC is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
4163
Gene Name (Vector)
mutated in colorectal cancers
Gene Symbol
MCC
HGNC ID
HGNC:6935
ORF Size (aa)
2490
ORF Size (bp)
2490 bp
RefSeq ID
NM_002387
RefSeq Synonyms
NM_002387, NM_001085377, BC018919, BC009279,
Species
human
UniGene ID
Hs.593171

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.