mouse CASP3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Casp3.
shADV-254558
Ad-m-CASP3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Casp3 (caspase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A830040C14Rik; AC-3; CASP-3; Caspase-3; CC3; CPP-32; CPP32; Lice; mldy; SCA-1; Yama
Description (Vector)
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp- -Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Gene ID
12367
Gene Name (Vector)
caspase 3
Gene Symbol
Casp3
ORF Size (aa)
834
ORF Size (bp)
834 bp
RefSeq ID
NM_009810
RefSeq Synonyms
NM_009810, NM_001284409, BC038825,
Species
mouse
UniGene ID
Mm.34405
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.