mouse CANX shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Canx.
shADV-254464
Ad-m-CANX-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Canx (calnexin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110069N15Rik; AI988026; Cnx; D11Ertd153e
Description (Vector)
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
Gene ID
12330
Gene Name (Vector)
calnexin
Gene Symbol
Canx
ORF Size (aa)
1776
ORF Size (bp)
1776 bp
RefSeq ID
NM_007597
RefSeq Synonyms
NM_007597, NM_001110500, NM_001110499, BC040244, BC012408,
Species
mouse
UniGene ID
Mm.248827
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.