mouse CALR shRNA silencing Adenovirus

Name
Ad-m-CALR-shRNA

Cat No
shADV-254432

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Calr.

shADV-254432

Ad-m-CALR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Calr (calreticulin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Calregulin; CRT

Description (Vector)

Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).

Gene ID

12317

Gene Name (Vector)

calreticulin

Gene Symbol

Calr

ORF Size (aa)

1251

ORF Size (bp)

1251 bp

RefSeq ID

NM_007591

RefSeq Synonyms

NM_007591, BC003453,

Species

mouse

UniGene ID

Mm.467043

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.