mouse MCMBP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Mcmbp.
shADV-254317
Ad-m-MCMBP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mcmbp (minichromosome maintenance complex binding protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110007A13Rik; AU017382; BC025641; MCM-BP
Description (Vector)
Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion.
Gene ID
210711
Gene Name (Vector)
minichromosome maintenance complex binding protein
Gene Symbol
Mcmbp
ORF Size (aa)
1929
ORF Size (bp)
1929 bp
RefSeq ID
NM_145955
RefSeq Synonyms
NM_145955, BC038342, BC025641,
Species
mouse
UniGene ID
Mm.58882
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.