mouse ATG4C shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Atg4c.
shADV-253223
Ad-m-ATG4C-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Atg4c (autophagy related 4C, cysteine peptidase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Apg4-C; Apg4c; Atg4cl; Autl1
Description (Vector)
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
Gene ID
242557
Gene Name (Vector)
autophagy related 4C, cysteine peptidase
Gene Symbol
Atg4c
ORF Size (aa)
1377
ORF Size (bp)
1377 bp
RefSeq ID
NM_175029
RefSeq Synonyms
NM_175029, NM_001145967, BC058981,
Species
mouse
UniGene ID
Mm.277366
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.