mouse ATG4B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Atg4b.
shADV-253222
Ad-m-ATG4B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Atg4b (autophagy related 4B, cysteine peptidase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2510009N07Rik; Apg4b; Atg4bl; Autl1; AW048066
Description (Vector)
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
Gene ID
66615
Gene Name (Vector)
autophagy related 4B, cysteine peptidase
Gene Symbol
Atg4b
ORF Size (aa)
1182
ORF Size (bp)
1182 bp
RefSeq ID
NM_174874
RefSeq Synonyms
NM_174874, BC027184,
Species
mouse
UniGene ID
Mm.29087
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.