mouse ARMET shRNA silencing Adenovirus

Name 
Ad-m-ARMET-shRNA
Cat No 
shADV-253056
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Manf.

shADV-253056
Ad-m-ARMET-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Manf (mesencephalic astrocyte-derived neurotrophic factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
3230402M22Rik; AA407711; AA408789; AA673178; Armet; D17914; D18Mgi17
Description (Vector)
Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Gene ID
74840
Gene Name (Vector)
mesencephalic astrocyte-derived neurotrophic factor
Gene Symbol
Manf
ORF Size (aa)
498
RefSeq ID
NM_029103
RefSeq Synonyms
NM_029103, BC048616,
Species
mouse
UniGene ID
Mm.29778

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.