mouse ARL6 shRNA silencing Adenovirus

Name 
Ad-m-ARL6-shRNA
Cat No 
shADV-253023
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Arl6.

shADV-253023
Ad-m-ARL6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Arl6 (ADP-ribosylation factor-like 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1110018H24Rik; 2210411E14Rik; BBS3
Description (Vector)
Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade. Isoform 2 may be required for proper retinal function and organization.
Gene ID
56297
Gene Name (Vector)
ADP-ribosylation factor-like 6
Gene Symbol
Arl6
ORF Size (aa)
561
RefSeq ID
NM_019665
RefSeq Synonyms
NM_019665, NM_001347244, BC018497,
Species
mouse
UniGene ID
Mm.392505

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.