mouse ARL2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Arl2.
shADV-253012
Ad-m-ARL2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Arl2 (ADP-ribosylation factor-like 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610009M23Rik; AI115441; AW553335
Description (Vector)
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle.
Gene ID
56327
Gene Name (Vector)
ADP-ribosylation factor-like 2
Gene Symbol
Arl2
ORF Size (aa)
555
RefSeq ID
NM_019722
RefSeq Synonyms
NM_019722, BC060259,
Species
mouse
UniGene ID
Mm.21071
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.