mouse APLF shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Aplf.
shADV-252821
Ad-m-APLF-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Aplf (aprataxin and PNKP like factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2010301N04Rik; AI452191
Description (Vector)
Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.
Gene ID
72103
Gene Name (Vector)
aprataxin and PNKP like factor
Gene Symbol
Aplf
ORF Size (aa)
1176
ORF Size (bp)
1176 bp
RefSeq ID
NM_024251
RefSeq Synonyms
NM_024251, NM_001170489, BC002179,
Species
mouse
UniGene ID
Mm.31770
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.