mouse ANAPC2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Anapc2.
shADV-252599
Ad-m-ANAPC2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Anapc2 (anaphase promoting complex subunit 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9230107K09Rik; AL024279; Apc2; Emi4; Imi4; mKIAA1406
Description (Vector)
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.
Gene ID
99152
Gene Name (Vector)
anaphase promoting complex subunit 2
Gene Symbol
Anapc2
ORF Size (aa)
2514
ORF Size (bp)
2514 bp
RefSeq ID
NM_175300
RefSeq Synonyms
NM_175300, BC137583,
Species
mouse
UniGene ID
Mm.291624
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.