mouse AKR1A4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Akr1a1.
shADV-252412
Ad-m-AKR1A4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Akr1a1 (aldo-keto reductase family 1, member A1 (aldehyde reductase)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610201A18Rik; Akr1a4
Description (Vector)
Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
Gene ID
58810
Gene Name (Vector)
aldo-keto reductase family 1, member A1 (aldehyde reductase)
Gene Symbol
Akr1a1
ORF Size (aa)
978
ORF Size (bp)
978 bp
RefSeq ID
NM_021473
RefSeq Synonyms
NM_021473, BC046762, BC039926,
Species
mouse
UniGene ID
Mm.30085
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.