mouse FER shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Fer.
shADV-252334
Ad-m-FER-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Fer (fer (fms/fps related) protein kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AV082135; C330004K01Rik; Fert; Fert2
Description (Vector)
Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide (LPS). Plays a role in synapse organization, trafficking of synaptic vesicles, the generation of excitatory postsynaptic currents and neuron-neuron synaptic transmission. Plays a role in neuronal cell death after brain damage. Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3, but the biological relevance of this depends on cell type and stimulus.
Gene ID
14158
Gene Name (Vector)
fer (fms/fps related) protein kinase
Gene Symbol
Fer
ORF Size (aa)
2298
ORF Size (bp)
2298 bp
RefSeq ID
NM_008000
RefSeq Synonyms
NM_008000, NM_001286415, NM_001037997, BC058100,
Species
mouse
UniGene ID
Mm.23039
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.