mouse ACER1 shRNA silencing Adenovirus

Name 
Ad-m-ACER1-shRNA
Cat No 
shADV-251907
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Acer1.

shADV-251907
Ad-m-ACER1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Acer1 (alkaline ceramidase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2310024P18Rik; AI662009; Alkcdase1; Asah3; Cer1
Description (Vector)
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. Has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. May have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids (By similarity).
Gene ID
171168
Gene Name (Vector)
alkaline ceramidase 1
Gene Symbol
Acer1
ORF Size (aa)
822
ORF Size (bp)
822 bp
RefSeq ID
NM_175731
RefSeq Synonyms
NM_175731, BC130254,
Species
mouse
UniGene ID
Mm.218784

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.