mouse ACD shRNA silencing Adenovirus

Name 
Ad-m-ACD-shRNA
Cat No 
shADV-251902
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Acd.

shADV-251902
Ad-m-ACD-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Acd (adrenocortical dysplasia). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role in organogenesis.
Gene ID
497652
Gene Name (Vector)
adrenocortical dysplasia
Gene Symbol
Acd
ORF Size (aa)
1251
ORF Size (bp)
1251 bp
RefSeq ID
NM_001012638
RefSeq Synonyms
NM_001012638, BC138695, BC138694,
Species
mouse
UniGene ID
Mm.12964

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.