mouse ABI2 shRNA silencing Adenovirus

Name 
Ad-m-ABI2-shRNA
Cat No 
shADV-251828
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Abi2.

shADV-251828
Ad-m-ABI2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Abi2 (abl-interactor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
8430425M24Rik; AI839867; C130078H13
Description (Vector)
ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA.
Gene ID
329165
Gene Name (Vector)
abl-interactor 2
Gene Symbol
Abi2
ORF Size (aa)
1341
ORF Size (bp)
1341 bp
RefSeq ID
NM_198127
RefSeq Synonyms
NM_198127, NM_001198571, NM_001198570, BC079646, BC079545, BC056345,
Species
mouse
UniGene ID
Mm.212066

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.