mouse ATF7IP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Atf7ip.
shADV-251384
Ad-m-ATF7IP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Atf7ip (activating transcription factor 7 interacting protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610204M12Rik; AM; Mcaf1
Description (Vector)
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Facilitates telomerase TERT and TERC gene expression by SP1 in cancer cells.
Gene ID
54343
Gene Name (Vector)
activating transcription factor 7 interacting protein
Gene Symbol
Atf7ip
ORF Size (aa)
3921
ORF Size (bp)
3921 bp
RefSeq ID
NM_019426
RefSeq Synonyms
NM_019426, BC060246, BC052460,
Species
mouse
UniGene ID
Mm.173271
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.