mouse 2410022L05RIK shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Coprs.
shADV-250740
Ad-m-2410022L05RIK-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Coprs (coordinator of PRMT5, differentiation stimulator). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1700029I03Rik; 2410022L05Rik; AA409325; AI256813; C85432; Copr5
Description (Vector)
Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression.
Gene ID
66423
Gene Name (Vector)
coordinator of PRMT5, differentiation stimulator
Gene Symbol
Coprs
ORF Size (aa)
522
RefSeq ID
NM_025556
RefSeq Synonyms
NM_025556, BC029192,
Species
mouse
UniGene ID
Mm.29063
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.