mouse 2010110P09RIK shRNA silencing Adenovirus

Name 
Ad-m-2010110P09RIK-shRNA
Cat No 
shADV-250556
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Chp2.

shADV-250556
Ad-m-2010110P09RIK-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Chp2 (calcineurin-like EF hand protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2010110P09Rik; Cbhp2
Description (Vector)
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.
Gene ID
70261
Gene Name (Vector)
calcineurin-like EF hand protein 2
Gene Symbol
Chp2
ORF Size (aa)
591
RefSeq ID
NM_027363
RefSeq Synonyms
NM_027363, BC119204, BC119202,
Species
mouse
UniGene ID
Mm.96997

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.