mouse KDM6B shRNA silencing Adenovirus

Name 
Ad-m-KDM6B-shRNA
Cat No 
shADV-250424
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Kdm6b.

shADV-250424
Ad-m-KDM6B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Kdm6b (KDM1 lysine (K)-specific demethylase 6B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1700064E03Rik; BC038313; Jmjd3; mKIAA0346
Description (Vector)
Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Gene ID
216850
Gene Name (Vector)
KDM1 lysine (K)-specific demethylase 6B
Gene Symbol
Kdm6b
ORF Size (aa)
4926
ORF Size (bp)
4926 bp
RefSeq ID
NM_001017426
RefSeq Synonyms
NM_001017426, BC075632,
Species
mouse
UniGene ID
Mm.261201

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.