mouse 1520402A15RIK shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Lurap1.
shADV-250218
Ad-m-1520402A15RIK-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Lurap1 (leucine rich adaptor protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1520402A15Rik; Lrp35a
Description (Vector)
Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway. In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, leading to MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin assembly in the lamella (By similarity).
Gene ID
68075
Gene Name (Vector)
leucine rich adaptor protein 1
Gene Symbol
Lurap1
ORF Size (aa)
720
ORF Size (bp)
720 bp
RefSeq ID
NM_026547
RefSeq Synonyms
NM_026547, BC147750, BC147737, BC147059, BC147058,
Species
mouse
UniGene ID
Mm.388915
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.