human MAPT shRNA silencing Adenovirus

Name 
Ad-h-MAPT-shRNA
Cat No 
shADV-233559
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human MAPT.

shADV-233559
Ad-h-MAPT-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MAPT (microtubule associated protein tau). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU
Description (Vector)
MAPT encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Gene ID
4137
Gene Name (Vector)
microtubule associated protein tau
Gene Symbol
MAPT
HGNC ID
HGNC:6893
ORF Size (aa)
1152
ORF Size (bp)
1152 bp
RefSeq ID
NM_005910
RefSeq Synonyms
NM_016841, NM_016835, NM_016834, NM_005910, NM_001203252, NM_001203251, NM_001123067, NM_001123066, BC114948,
Species
human

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.