human RNF103 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RNF103.
shADV-231687
Ad-h-RNF103-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RNF103 (ring finger protein 103). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HKF-1; KF-1; KF1; ZFP-103; ZFP103
Description (Vector)
RNF103 contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene.
Gene ID
7844
Gene Name (Vector)
ring finger protein 103
Gene Symbol
RNF103
HGNC ID
HGNC:12859
ORF Size (aa)
2058
ORF Size (bp)
2058 bp
RefSeq ID
NM_005667
RefSeq Synonyms
NM_005667, NM_001198952, NM_001198951, BC110333, BC035053,
Species
human
UniGene ID
Hs.469199
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.