human VNN1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human VNN1.
shADV-230270
Ad-h-VNN1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human VNN1 (vanin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HDLCQ8; Tiff66
Description (Vector)
VNN1 encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. VNN1 lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.
Gene ID
8876
Gene Name (Vector)
vanin 1
Gene Symbol
VNN1
HGNC ID
HGNC:12705
ORF Size (aa)
1542
ORF Size (bp)
1542 bp
RefSeq ID
NM_004666
RefSeq Synonyms
NM_004666, BC096268, BC096267, BC096266, BC096265,
Species
human
UniGene ID
Hs.12114
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.