human UGT1A5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human UGT1A5.
shADV-230235
Ad-h-UGT1A5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human UGT1A5 (UDP glucuronosyltransferase family 1 member A5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
UDPGT; UDPGT 1-5; UGT1E
Description (Vector)
UGT1A5 encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. UGT1A5 is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter.
Gene ID
54579
Gene Name (Vector)
UDP glucuronosyltransferase family 1 member A5
Gene Symbol
UGT1A5
HGNC ID
HGNC:12537
ORF Size (aa)
1602
ORF Size (bp)
1602 bp
RefSeq ID
NM_019078
RefSeq Synonyms
NM_019078, BC141470,
Species
human
UniGene ID
Hs.
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.

