human RNF31 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RNF31.
shADV-230057
Ad-h-RNF31-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RNF31 (ring finger protein 31). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E3 ubiquitin-protein ligase RNF31; HOIL-1-interacting protein; HOIP; Paul; RING finger protein 31; RING-type E3 ubiquitin transferase RNF31; ZIBRA; zinc in-between-RING-finger ubiquitin-associated domain protein
Description (eCommerce)
RING finger protein 31 is an E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96EP0].
Description (Vector)
RNF31 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.
Gene ID
55072
Gene Name (eCommerce)
ring finger protein 31
Gene Name (Vector)
ring finger protein 31
Gene Symbol
RNF31
HGNC ID
HGNC:16031
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3219
ORF Size (bp)
3219 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase RNF31
RefSeq ID
NM_017999
RefSeq Synonyms
NM_017999, NM_001310332, BC017376, BC012077,
Research Areas
CD40 Signaling,Immunology,NF-kB Signaling,Signal Transduction,T-cell Receptor Signaling,Toll-like Receptor Signaling,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology,immunology,signal_transduction
Species
human
Target Sentence
RING finger protein 31 is an E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96EP0].
UniGene ID
Hs.375217
UniProt ID (eCommerce)
Q96EP0
Recently Viewed Products
Ad-h-LRRC23-shRNA
Cat No: shADV-214530
Ad-r-RGD1307537-shRNA
Cat No: shADV-291539
Ad-h-SFRS14-shRNA
Cat No: shADV-222793
AAV-r-TSSK5
Cat No: AAV-293235
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.