human ARHGAP8 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ARHGAP8.
shADV-229574
Ad-h-ARHGAP8-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ARHGAP8 (Rho GTPase activating protein 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BPGAP1; PP610
Description (Vector)
ARHGAP8 encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Gene ID
23779
Gene Name (Vector)
Rho GTPase activating protein 8
Gene Symbol
ARHGAP8
HGNC ID
HGNC:677
ORF Size (aa)
1302
ORF Size (bp)
1302 bp
RefSeq ID
NM_001017526
RefSeq Synonyms
NM_181335, NM_001198726, NM_001017526, BC048280,
Species
human
UniGene ID
Hs.
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.