human ZFYVE27 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ZFYVE27.
shADV-228241
Ad-h-ZFYVE27-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ZFYVE27 (zinc finger FYVE-type containing 27). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PROTRUDIN; SPG33
Description (Vector)
ZFYVE27 encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
Gene ID
118813
Gene Name (Vector)
zinc finger FYVE-type containing 27
Gene Symbol
ZFYVE27
HGNC ID
HGNC:26559
ORF Size (aa)
1236
RefSeq ID
NM_001002261
RefSeq Synonyms
NM_144588, NM_001174122, NM_001174121, NM_001174120, NM_001174119, NM_001002262, NM_001002261, BC030621,
Species
human
UniGene ID
Hs.523194
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.