human YWHAZ shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human YWHAZ.
shADV-228009
Ad-h-YWHAZ-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
14-3-3-zeta; HEL-S-3; HEL-S-93; HEL4; KCIP-1; YWHAD
Description (Vector)
YWHAZ product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
Gene ID
7534
Gene Name (Vector)
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
Gene Symbol
YWHAZ
HGNC ID
HGNC:12855
ORF Size (aa)
738
RefSeq ID
NM_003406
RefSeq Synonyms
NM_145690, NM_003406, NM_001135702, NM_001135701, NM_001135700, NM_001135699, BC111951, BC108281, BC101483, BC099904, BC083508, BC072426, BC068456, BC063824, BC003623,
Species
human
UniGene ID
Hs.492407
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.